Drug repurposing and human parasitic protozoan diseases

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Drug repurposing and human parasitic protozoan diseases

Parasitic diseases have an enormous health, social and economic impact and are a particular problem in tropical regions of the world. Diseases caused by protozoa and helminths, such as malaria and schistosomiasis, are the cause of most parasite related morbidity and mortality, with an estimated 1.1 million combined deaths annually. The global burden of these diseases is exacerbated by the lack ...

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Repurposing human Aurora kinase inhibitors as leads for anti-protozoan drug discovery.

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1 Department of Pharmacognosy, Faculty of Pharmacy and Biochemistry, University of Buenos Aires, 1113 Buenos Aires, Argentina 2Unitat de Farmacologia i Farmacognòsia, Facultat de Farmàcia, Universitat de Barcelona, 08028 Barcelona, Spain 3 Universidade do Vale do Itajaı́, Núcleo De Investigações Quı́mico-Farmacêuticas (NIQFAR), CCS, Brazil 4Department of Chemistry, University of Alabama in Huntsv...

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ژورنال

عنوان ژورنال: International Journal for Parasitology: Drugs and Drug Resistance

سال: 2014

ISSN: 2211-3207

DOI: 10.1016/j.ijpddr.2014.02.002